Forensic Medicine Model Question

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Model Question on Forensic Medicine

1. Which of the following toxins is not produced by bacteria ?
(1) Cholera toxin
(2) Aflatoxin
(3) Botulinum toxin
(4) Tetanus toxin

2. Thalidomide is known for its ________ effects.
(1) Teratogenic
(2) Carcinogenic
(3) Mutagenic
(4) Hepatotoxic

3. Why activated charcoal is administered in case of oral poisoning ?
(1) It deactivates toxicants.
(2) It increases the metabolic processes of detoxification.
(3) It chemically detoxifies the toxicants.
(4) It reduces absorption of toxicants by adsorbing them.

4. In ‘comet assay’ we measure the
(1) Extent of hepatotoxicity
(2) Extent of damage in renal tubules
(3) Extent of DNA damage in single cells
(4) Pancreatic damage

5. Tetany can be caused by poisoning with
(1) Strychnine
(2) Curare
(3) Oxalates
(4) Carbamates

6. “Wet blotting paper” appearance of stomach mucosa occurs due to ingestion of
(1) H2SO4 poisoning
(2) Oxalic acid poisoning
(3) Arsenic poisoning
(4) MgSO4 poisoning

7. Calcium disodium edentate can be used as an antidote for
(1) Oxalic acid
(2) Lead acetate
(3) Ammonium chloride
(4) Copper sulphate

8. Which one of the following are the main targets of lead toxicity ?
(1) Liver and kidneys
(2) Nervous system and hematopoietic system
(3) Bones and muscles
(4) Skin and hair

9. Poisoning by a metallic poison happened. What is the reason of toxic action of metallic poisons ?
(1) Binding with lipids
(2) Binding with amino acids, proteins and polypeptides
(3) Binding with hydrochloric acid
(4) Binding with cholesterol

10. Burtonian line is seen with poisoning of
(1) Mercury
(2) Lead
(3) Arsenic
(4) Zinc

11. Following is a key factor in the treatment of aspirin poisoning :
(1) Gastric lavage
(2) Forced alkaline dieresis
(3) Antidotes
(4) Conservative management

12. An industrial worker goes to a dermatologist troubled by patchy pigmentation on the skin of his hands with hyperkeratosis also seen on some areas. Exposure of what substance could cause that ?
(1) Arsenic
(2) Lead
(3) Oxalic acid
(4) Metallic Copper

13. Autopsy in case of poisoning of a 50 years old is being done. Upon opening, | the stomach mucosa appears hard and leathery. Suspected agent would be
(1) Carbolic acid
(2) Salicylic acid
(3) Nitric acid
(4) Hydrochloric acid

14. A middle aged man presents with paraesthesia of hand and feet. Examination reveals presence of ‘Mees’ lines in the nails and rain drop pigmentation in the hands. The most likely causative toxin for the above mentioned symptoms is
(1) Lead
(2) Arsenic
(3) Thallium
(4) Mercury

15. One of the following does not result from Mercury poisoning
(1) Wilson’s disease
(2) Minimata disease
(3) Kawasaki disease
(4) Pink disease

16. Acrodynia is associated with
(1) Mercury
(2) Phenolic acid
(3) Oxalic acid
(4) Carbolic acid

17. A 12-year-old boy had an alleged history of snake bite and presented to the hospital with inability to open eyes well and difficulty in breathing. He is very anxious and is having tachycardia and tachypnea. On examination bite mark cannot be visualized and there is no swelling of the limb. He has bilateral ptosis. His 20 min whole blood clotting test is good quality. What is the next course of action ?
(1) Don’t give Anti-Snake Venom (ASV), but observe the patient
(2) Give ASV and keep the patient in observation
(3) Give ASV, and give neostigmine and observe the patient
(4) Reassure the patient and send him home with anxiolytic

18. The most useful bedside test to suggest snake bite envenomation is
(1) Prothrombin time
(2) 20 min whole blood clotting time
(3) International normalized ratio
(4) Platelet count

19. Antidote of organophosphate insecticide
(1) Physostigmine
(2) Naloxone
(3) Pralidoxime
(4) N. Acetylecysteine

20. Organo phosphorous compounds act by
(1) Stimulating acetylcholine esterase
(2) Inhibiting acetylcholine esterase
(3) Stimulating acetylcholine receptors
(4) Stimulating acetylcholine synthesis

21. Intermediate syndrome
(1) Is caused by carbamate poisoning
(2) Responds to oximes
(3) Affects distal limb muscles
(4) Is due to long lasting cholinesterase inhibition and muscle necrosis

22. Most specific test for organo phosphorous compounds poisoning is
(1) RBC cholinesterase
(2) Plasma cholinesterase
(3) RBC uroporphyrin level
(4) Scrum level of organo phosphorous compounds

23. For the purpose of estimation of blood cholinesterase level, blood should be collected only in
(1) Sodium chloride
(2) Sodium fluoride
(3) Heparinised tube
(4) Potassium oxalate

24. Kraits (Kalach) have which type of venom ?
(1) Neurotoxic
(2) Hematotoxic
(3) Both
(4) None

25. No bite mark, No local sign, Snake not seen, Neurotoxic features present. What is the most correct Diagnosis ?
(1) Scorpion bite
(2) Cobra bite
(3) Krait bite
(4) Viper bite

26. Polyvalent ASV is available at
(1) District hospitals
(2) At Medical Colleges
(3) At all Govt. Hospitals
(4) Atsome special hospitals only

27. A 39-year-old carpenter has taken two bottles of liquor from the local shop. After about an hour, he develops confusion, vomiting and blurring of vision. He has been brought to the emergency department. He should be given
(1) Naloxone
(2) Diazepam
(3) Flumazelnil
(4) Ethyl alcohol

28. Magnan’s symptoms are characteristic symptoms with which poisoning ?
(1) Alcohol
(2) Charas
(3) Cocaine
(4) Ecstasy

29. Smack is
(1) Cocaine
(2) LSD
(3) Heroin
(4) Cannabis

30. What is the most common toxicity target of ethanol (beverage alcohol) in humans ?
(1) Brain
(2) Fetus
(3) Liver
(4) Kidneys

31. Opioids like heroin and morphine can cause death by
(1) CNS depression
(2) Cardiac failure
(3) Respiratory depression and failure
(4) Renal failure

32. One of the following drugs imparts a “pear-like” odour to the breath in overdose
(1) Alprazolam
(2) Amitryptiline
(3) Chloramphenicol
(4) Chloral hydrate

33. “Cold turkey” refers to manifestations resulting from
(1) Food poisoning
(2) Hypothermia
(3) Eating frozen turkey
(4) Opium withdrawal

34. The drug of choice for detoxifying a morphine addict is
(1) Methadone
(2) Naloxone
(3) Nalmefene
(4) Amiuphenazole

35. A young male was brought by police from the railway platform to you. He is talking irrelevant. He is having dry mouth, hot skin, dilated pupils, staggering gait and slurred speech. What is your most probable diagnose ?
(1) Organophosphorous poisoning
(2) Carbamates poisoning
(3) Dhatura poisoning
(4) Alcohol intoxication

36. A 19 year old female presents to the emergency department with complain of abdominal pain. The patient gave a history of episodes of tearfulness since 2 weeks for which she was taking some medications. On barium studies an intraluminal filling defect is seen. CT shows mobile intragastric mass consisting of “compressed concentric rings”. Exploratory laparotomy was conducted for the same. The toxicological profile would be probably positive for
(1) Quinine
(2) TCAs
(3) Dopamine
(4) Aspirin

37. Morphine poisoning can be differentiated from pethidine poisoning by
(1) Urine output
(2) Heart rate
(3) Diameter of pupils
(4) Blood pressure

38. What is the mode of action of carbon monoxide (CO) ?
(1) It reduces the oxygen absorption by directly or indirectly damaging the alveoli.
(2) Combines with hemoglobin to reduce oxygen carrying capacity of RBCs.
(3) It has a corrosive effect on airways, specially bronchi and bronchioles.
(4) It alters the structure of the hemoglobin.

39. Rigor mortis is rapid and for short duration in which of the following ?
(1) Strychnine poisoning
(2) Alcohol
(3) Cocaine poisoning
(4) Lead poisoning

40. Which is not a feature of aconite poisoning ?
(1) Chest pain
(2) Increased blood pressure
(3) Tingling and numbness
(4) Hypersalivation

41. At autopsy, the stomach contents emits bitter Almond smell, I could be a case of
(1) Cyanide poisoning
(2) Thorn apple poisoning
(3) Bitter apple poisoning
(4) Carbolic acid poisoning

42. Asphyxiants causes
(1) Failure of respiratory centre
(2) Paralysis of respiratory muscles
(3) Prevent use of oxygen at tissue level
(4) All of these

43. Poison acting by post synaptic block is
(1) Strychnine
(2) Oleander
(3) Ricinus
(4) Papaver

44. Pinkish PM staining suggestive of
(1) CO poisoning
(2) Phosphene
(3) Hydrogen sulphide
(4) Carbon dioxide

45. Agent which causes failure of respiratory centre
(1) Carbon dioxide
(2) Phosgene
(3) CO
(4) HCN