General Medicine Previous Year Question
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Previous Year Question of General Medicine
1. Which characteristic feature is seen in kidney of malignant hypertension
(1) Hyaline arteriosclerosis
(2) Fibrinoid necrosis
(3) Medial wall hyperplasia
(4) Coagulative necrosis
2. Salt loosing nephropathy is seen in
(1) Amyloidosis of kidney
(2) Interstitial nephritis
(3) Poly cystic kidney disease
(4) Lupus nephritis
3. All of the following are decrease in nephrotic syndrome except
(1) Thyroxine binding globulin
(2) Ceruloplasmin
(3) Fibrinogen
(4) Transferrin
4. Which of the following is not a precipitating factor for hepatic encephalopathy in patients with chronic liver disease
(1) Hypokalemia
(2) Azotemia
(3) GIT bleeding
(4) Metabolic acidosis
5. Chylous ascites is caused by all the following except
(1) Tuberculosis
(2) Filariasis
(3) Nephrotic syndrome
(4) Cirrhosis
6. Conjugated hyperbilirubinemia is seen in
(1) Gilbert’s syndrome
(2) Criggler Najjar syndrome
(3) Dubin Johnson syndrome
(4) Haemolytic anaemia
7. Ratio of AST/ALT >1 is present in
(1) Drug hepatitis
(2) Alcoholic hepatitis
(3) Acute viral hepatitis
(4) All of the above
8. Non parentral hepatitis is
(1) Hepatitis E
(2) Hepatitis B
(3) Hepatitis C
(4) Hepatitis D
9. COUNCIL MAN bodies are seen in
(1) Bronchial asthma
(2) Alzheimer’s disease
(3) Acute viral hepatitis
(4) Hodgkins lymphoma
10. Most common Initial symptom of primary biliary cirrhosis
(1) Pruritis
(2) Hyperpigmentation
(3) Jaundice
(4) Steatorrhoea
11. H.Pylori is known to cause
(1) Antral gastritis
(2) Peptic ulcer
(3) Gastric MALT lymphoma
(4) All the above
12. Elevated serum amylase level seen in all except
(1) Glomerulonephritis
(2) Ruptured ectopic pregnancy
(3) Peritonitis
(4) Postoperative
13. RANSON’S criteria for prognosis of acute pancreatitis are all except
(1) Serum ALT > 500 IU/L
(2) Age >55 years
(3) Hyperglycaemia >200mg/dl
(4) Leucocytosis >16,000/uL
14. Martel’s sign is seen in
(1) Sjogren’s syndrome
(2) Tophaceous gout
(3) Giant cell arteritis
(4) Henoch schonlein purpura
15. Scleroderma most commonly involves
(1) Esophagus
(2) Stomach
(3) Duodenum
(4) Descending colon
16. The treatment of choice in Wegner’s granulomatosis among the following
(1) Cyclophosphamide
(2) Levofloxacin
(3) Ampicillin-sulbactam
(4) Chloroquine
17. Felt’s syndrome include all except
(1) Ankylosing spondylitis
(2) Splenomegaly
(3) Rheumatoid arthritis
(4) Neutropenia
18. In polyarteritis nodosa, aneurysms are seen in all, except
(1) Kidney
(2) Liver
(3) Lung
(4) Spleen
19. Kawasaki disease is associated with all of the following except
(1) Strawberry tongue
(2) Cervical lymphadenopathy
(3) Thrombocytopenia
(4) Coronary artery aneurysm
20. pANCA is sensitive and specific for
(1) Kawasaki disease
(2) Idiopathic crescentric Glomerulonephritis
(3) Wegner’s Granulomatosis
(4) Behcet’s disease
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21. Joint erosions is not a feature of
(1) Osteoarthritis
(2) Psoriasis
(3) Gout
(4) Systemic lupus erythematosus
22. Causes of Charcoat’s joint includes all the following except
(1) Syringomyelia
(2) Tabes dorsalis
(3) Diabetes
(4) Arthrogryposis multiplex congenita
23. Indication of systemic steroids in rheumatoid arthritis
(1) Carpel tunnel syndrome
(2) Presence of deformities
(3) Endocarditis
(4) Articular cartilage involvement
24. Syndrome of Inappropriate secretion of Antidiuretic hormone (SIADH) is seen in all except
(1) Multiple sclerosis
(2) Interstitial Nephritis
(3) Use of Tricyclic antidepressant drugs
(4) Bronchial adenoma
25. Dilutional hyponatremia is seen in
(1) Addison’s disease
(2) Diabetes insipidus
(3) Diuretic therapy
(4) None
26. Somogyi phenomenon is
(1) Hyperglycemia followed by hypoglycemia
(2) Hypoglycemia followed by hyperglycemia
(3) Renal glycosuria
(4) Nonketotic hyperosmolar hyperglycaemia
27. All the following are features of primary hyperaldosteronism except
(1) Pedal edema
(2) Hypokalemia
(3) Hyposecretion of renin
(4) Diastolic Hypertension
28. Which is not a clinical feature of Addison’s disease ?
(1) Hypoglycemia
(2) Acidosis
(3) Hypocalcemia
(4) Hyperkalemia
29. All are clinical features of pheochromocytoma except
(1) Profuse sweating
(2) Orthostatic hypotension
(3) Hypocalcemia
(4) Paroxysmal hypertension
30. Hypercalcemia is not a feature of one of the following
(1) Hyperthyroidism
(2) Lithium therapy
(3) Tumor lysis syndrome
(4) Thiazides
31. The characterisitic commonest presentation of diabetic neuropathy is
(1) Distal symmetrical sensory neuropathy
(2) Isolated third cranial nerve palsy
(3) Pure motor neuropathy
(4) Autonomic neuropathy
32. Insulin resistance is seen in all except
(1) Obesity
(2) Addison’s disease
(3) Werner’s syndrome
(4) Pheochromocytoma
33. All the following are features of thyrotoxicosis except
(1) Diastolic murmur
(2) Wide pulse pressure
(3) Atrial fibrillation
(4) Means-Lerman scratch sound in systole
34. Insulin resistance syndrome includes all except
(1) Dyslipidemia
(2) Hypertension
(3) Congestive Heart Failure
(4) Abdominal Obesity
35. All cause weight gain except
(1) Pheochromocytoma
(2) Insulin secreting tumor
(3) Hypothyroidism
(4) Cushing syndrome
36. Hypoglycemia is a recognized feature of all the following conditions except
(1) Renal failure
(2) Acromegaly
(3) Addison’s disease
(4) Sepsis
37. Most useful investigation in diagnosis of diabetic ketoacidosis
(1) Urine sugar
(2) Urine ketones
(3) Ketonemia
(4) pH of blood
38. All are useful in painful diabetic neuropathy except
(1) Gabapentin
(2) Carbamazepine
(3) Dextroamphetamine
(4) Nortryptiline
39. Life threatening complications of diabetes are all except
(1) Emphysematous pyelonephritis
(2) Rhinocerebral mucormycosis
(3) Malignant otitis externa
(4) Emphysematous appendicitis
40. The characterisitic finding in diabetic nephropathy
(1) Diffuse glomerulosclerosis
(2) Nodular glomerulosclerosis
(3) Glomerular capillary basement membrane thinning
(4) Lipid caps
41. Ultra short acting insulin
(1) Insulin Glulisine
(2) Insulin Lispro
(3) Insulin Aspart
(4) All the above
42. Intensive management of diabetes is needed in all except
(1) Post renal transplant in diabetic nephropathy
(2) Diabetes with acute coronary syndrome
(3) Diabetes with septicaemia
(4) Diabetes with autonomic neuropathy causing postural hypotension
43. For Dipeptidyl peptidase IV inhibitors (DPP4), mechanism of action all are true except
(1) Prolong endogenous GLP-1 action
(2) Increase insulin
(3) Decrease glucagon
(4) Decrease insulin resistance
44. Absent ankle jerk and extensor plantar response is found in
(1) Sub acute combined degeneration
(2) Vitamin B12 deficiency
(3) Tabes dorsalis
(4) Friedrich’s ataxia
45. The characteristic feature of a frontal lobe tumor is
(1) Ataxia
(2) Urinary incontinence
(3) Aphasia
(4) Antisocial behaviour
46. All are features of tabes dorsalis, except
(1) Urinary incontinence
(2) Argyll Robertson Pupil
(3) Lightning pains
(4) Hyperreflexia
47. Drug of choice for Absence seizures
(1) Phenytoin
(2) Lamotrigine
(3) Sodium Valproate
(4) Carbamazepine
48. Hemiplegia is most commonly caused by thrombosis of
(1) Middle cerebral artery
(2) Posterior cerebral artery
(3) Anterior cerebral artery
(4) Vertebral artery
49. A medial temporal lobe lesion produces
(1) Prosopagnosia
(2) Anomia
(3) Apraxia
(4) Anterograde amnesia
50. Lateral medullary syndrome (Wallenberg’s syndrome) is characterized by all, except
(1) Vertigo
(2) Diminished gag reflex
(3) Crossed hemianaesthesia
(4) Horner’s syndrome is rare
51. All of the following statements are true about Benedikt’s syndrome except
(1) Lesion at the level of Medulla
(2) Contralateral ataxia
(3) Ipsilateral third nerve palsy
(4) Involvement of basilar artery
52. A non-diabetic, non hypertensive adult male develops sudden severe headache, with altered sensorium, likely diagnosis is
(1) Migraine
(2) Subarachnoid haemorrhage
(3) Brain tumor
(4) Menningitis
53. Most common nerve involved in intracranial aneurysm is
(1) Trochlear
(2) Vestibulo cochlear
(3) Fascial
(4) Oculomotor
54. Neuropathy is not seen in
(1) Tuberculosis
(2) Leprosy
(3) Diabetes Mellitus
(4) Amyloidosis
55. Pure motor paralysis is seen in
(1) Sjogren’s syndrome
(2) Poliomyelitis
(3) Diabetes mellitus
(4) Leprosy
56. All causes descending motor paralysis, except
(1) Botulinum
(2) Diphtheria
(3) Guillan Barre syndrome
(4) Polio
57. Thymoma is associated with
(1) Multiple myeloma
(2) Tuberculosis
(3) Mysthaenia gravis
(4) Multiple sclerosis
58. Primary idiopathic polymyositis does not involve
(1) Pelvic girdle muscles of lower limb
(2) Pharyngeal muscles
(3) Ocular muscles
(4) Proximal muscles of upper limb
59. Gene for myotonic dystrophy is coded on chromosome number
(1) 17
(2) 19
(3) 21
(4) 28
60. All the following are known predisposing factors for Alzheimer’s disease except
(1) Female sex
(2) Age > 65 years
(3) Down-syndrome
(4) Smoking
